I am currently
completing my doctoral degree in biological anthropology at
New York University, part of the New York Consortium in
Evolutionary Primatology (NYCEP).
Research
Focus
Primate
Innate Immune Defense and Adaptation to Viral
Infection
It is well recognized that adaptive responses to
environmental pressures can influence a primate’s genome,
morphology or even behavior. Pathogens, specifically
viruses, have been part of the primate environment for
millions of years and variation observed in primate
susceptibility to viral infection and disease suggests that
the genomes of some primates are better adapted to co-exist
with certain viruses. In order to understand these
adaptations, my dissertation research explores the
evolutionary history of a selection of genes (including
TLR7, MyD88, and RIG-I) involved in the immune system
across a wide cross-section of primates.
Primate
Molecular Systematics
I have been involved in a number of research projects using
mitochondrial sequence to examine the molecular phylogeny
of the living primates. My M.A. thesis research used whole
mitochondrial genome sequence of eight colobines (or leaf
–eating monkeys) to infer the evolutionary relationships
among the genera of the subfamily Colobinae. My results
support a monophyletic clade of odd-nosed colobines
consisting of Nasalis,
Pygathrix,
and Rhinopithecus.
These data have been published in Molecular
Phylogenetics and Evolution (see publications below).
Recent
Publications
Sterner KN, RL Raaum, Y-P Zhang, C-B Stewart, TR Disotell.
2006. Mitochondrial
data support an odd-nosed colobine clade.
Molecular
Phylogenetics and Evolution. 40(1): 1-7.
Raaum RL, KN Sterner, CM Noviello, C-B Stewart, TR
Disotell. 2005. Catarrhine primate divergence dates
estimated from complete mitochondrial genomes: concordance
with fossil and nuclear DNA evidence. Journal
of Human Evolution. 48(3): 237-57.
Wildman DE, TJ Bergman, A al-Aghbari, KN Sterner, TK
Newman, JE Phillips-Conroy, CJ Jolly, TR Disotell. 2004.
Mitochondrial evidence for the origin of hamadryas
baboons. Molecular
Phylogenetics and Evolution. 32(1): 287-96.
Telfer PT, S Souquiere, SL Clifford, KA Abernethy, MW
Bruford, TR Disotell, KN Sterner, P Roques, PA Marx, EJ
Wickings. 2003. Phylogenetic divergence in
mandrills. Molecular
Ecology. 12(7): 2019-24.