NYCEP Alumnus Profile

Samuel Marquez

Assistant Professor Department of Cell Biology SUNY Downstate Medical Center


Ph.D. 2001, City University of New York



Tel: (718) 270-7455

Fax: (718) 270-2292

Overview of Research

Dr. Márquez is a functional craniofacial comparative anatomist whose research interests are in the evolution of the nose and paranasal sinuses and its clinical relevance particularly in the area of sinusitis. He is grounded in traditional gross anatomic dissection, morphometrics of dry skulls, andCT & MR imaging to understand human diversity of living populations. Dr. Márquez research has taken him to museums in Central and South America, Europe and the US to examine and measure diversity across numerous skull specimens housed in their osteological collections. Research goals are centered on questions concerning human origins that are driven by the theme of primate and human evolution with direct relevance to clinical consequences. He has scanned a large number of crania housed in the Division of Anthropology and Mammalogy at the American Museum of Natural History including Egyptian mummies dating to the predynastic era circa 3,600 B.C.E. as well as a Homo erectus calvaria from Indonesia catalogued as Sambungmachan 3 calvaria (SM-3). Dr. Márquez and the team he assembled in 2001 published in The Anatomical Record journal three papers on this curious fossil specimen. Findings were covered in both the international and national press that included The New York Times and NewsDay from New York and from El Tiempo and El Colombiano from the cities of Bogota and Cali in Colombia, South America.


Laitman JT, Reidenberg JS, Márquez S, and Gannon PJ (1996) What the nose knows: New Understandings of Neanderthal Upper Respiratory tract specializations Proc. Natl. Acad. Sci. USA 93:10543-10545

Gannon PJ, Doyle WJ, Ganjian E, Gnoy AR, Márquez S, Gabrielle HS, and Lawson W. (1997) Maxillary Sinus Mucosal Bloodflow During Nasal Versus Tracheal Respiration. Arch. Otolaryngol. Head Neck Surg. Vol. 123: 1326-1340.

Gannon PJ, Constantino P, Lueg EA, Chaplin MB, Brandwein MS, Passalaqua J, Fliegelman LJ, Laitman JT, Márquez S, and Urken M. (1999) Use of the Peritracheal Fold in the Dog Tracheal
Transplantation Model. Arch. Otolaryngol. Head Neck Surg. Vol. 125: 959-963.

Márquez S, Mowbray K, Sawyer GJ, Jacob T, and Silvers A (2001) A new fossil hominin calvaria from Indonesia – Sambungmacan 3. Anat. Rec. 262: 344-368.

Broadfield D, Holloway RL, Mowbray K, Silvers A, and Márquez S (2001) The endocast of Sambungmacan 3, a new Homo erectus from Java. Anat. Rec. 262: 369-379.

Delson E, Harvati K, Reddy D, Marcus LF, Mowbray K, Sawyer GJ, Jacob T, and Márquez S (2001)
The Sambungmacan 3 Homo erectus calvaria: a comparative morphometric and morphological analysis. Anat. Rec. 262: 380-397.

Mowbray K, Márquez S, and Delson E (2002) The Mandibular Fossa of Sm 3: A reply to Durband. Anat. Rec. 266: 142-145.

Antón SC, Márquez S, and Mowbray K (2002) Sambungmacan 3 and Cranial Variation in Asian Homo erectus. J. Human Evol. 43:555-562.

Márquez S (2008) The Paranasal Sinuses: The Last Frontier in Craniofacial Biology. Guest Editor of Anat. Rec. 291:1350-1361.

Márquez S and Laitman JT (2008) Climatic effects of the nasal complex: A CT imaging, comparative anatomical and morphometric investigation of Macaca mulatta and Macaca fascicularis. Anat. Rec. 291:1420-1445.

Márquez S, Tessema B, Clement P, and Schaefer SD (2008) Development of the ethmoid sinus and migration of extramural cells: The anatomical basis for this paranasal sinus. Anat. Rec. 291:1535-1553.